Most of my storylines shouldn't affect everyone else as such. A few notable events:
The Keep will finally deal with Baron Calephas, but I haven't decided when.
A Questioner will take up permanent residence at Metamor (this fits into Drift's story line too).
All the wrapup that will need to take place after LToY. For instance, Marigund will be forced to play host to Father Akaleth so they can learn what happened in Yesulam. That'll be a fun little meeting.
Then there's going to be Metamor becoming involved with the situation between Kelewair and Salinon and the heir to Kelewair being held prisoner in Salinon as well as a startling revelation about one of the Keep's own.
Charles will get some land.
The Rats put their plans to corner the caravan market into action.
The Valley gets some more Ecclesia priests and a nunnery.
Just some of the stuff I'm thinking about.
Dominus tecum